THCV (Tetrahydrocannabivarin)
/tet-ruh-hy-dro-kuh-NAB-ih-var-in/
A homologue of THC with a propyl side chain instead of a pentyl chain. Acts as a CB1 antagonist at low doses and partial agonist at high doses.
In Depth
THCV is found in higher concentrations in African sativa strains. Unlike THC, low doses of THCV may suppress appetite (CB1 antagonism), making it of interest for metabolic disorders and diabetes. At higher doses it can produce psychoactive effects. Early clinical trials suggest potential for glycemic control in type 2 diabetes.
Related Terms
Further Reading
More in Cannabinoids
Cannabidiol (CBD)
A non-intoxicating phytocannabinoid found in Cannabis sativa. The second most abundant cannabinoid in most cannabis strains.
Tetrahydrocannabinol (THC)
The primary psychoactive cannabinoid in cannabis. A partial agonist at CB1 and CB2 receptors.
Cannabigerol (CBG)
A non-intoxicating cannabinoid often called the "mother cannabinoid" — the biosynthetic precursor from which THC, CBD, and CBC are synthesized.
Cannabinol (CBN)
A mildly psychoactive cannabinoid formed by the oxidative degradation of THC. Accumulates as cannabis ages or is exposed to heat and light.
Cannabichromene (CBC)
A non-intoxicating phytocannabinoid that does not bind significantly to CB1 or CB2 receptors but interacts with TRP channels.