Cannabigerol (CBG)
/kan-uh-bih-JER-ol/
A non-intoxicating cannabinoid often called the "mother cannabinoid" — the biosynthetic precursor from which THC, CBD, and CBC are synthesized.
In Depth
CBG is present in low concentrations (<1%) in most cannabis strains. It acts as a partial agonist at CB1 and CB2 receptors, an α2-adrenoceptor agonist, and a 5-HT1A antagonist. Preclinical research suggests potential in inflammatory bowel disease, glaucoma, and as an antibacterial agent. Human clinical trials remain limited.
Related Terms
Further Reading
More in Cannabinoids
Cannabidiol (CBD)
A non-intoxicating phytocannabinoid found in Cannabis sativa. The second most abundant cannabinoid in most cannabis strains.
Tetrahydrocannabinol (THC)
The primary psychoactive cannabinoid in cannabis. A partial agonist at CB1 and CB2 receptors.
Cannabinol (CBN)
A mildly psychoactive cannabinoid formed by the oxidative degradation of THC. Accumulates as cannabis ages or is exposed to heat and light.
Cannabichromene (CBC)
A non-intoxicating phytocannabinoid that does not bind significantly to CB1 or CB2 receptors but interacts with TRP channels.
Phytocannabinoid
Any cannabinoid produced naturally by the cannabis plant. Distinct from endocannabinoids (produced by the body) and synthetic cannabinoids.