Cannabinol (CBN)
/kan-uh-bih-NOL/
A mildly psychoactive cannabinoid formed by the oxidative degradation of THC. Accumulates as cannabis ages or is exposed to heat and light.
In Depth
CBN has approximately 10% of the potency of THC at CB1 receptors. It is often marketed as a sleep aid, though clinical evidence for this specific effect is limited. CBN does show activity at TRPV2 channels and may have analgesic and anti-inflammatory properties. Its sedative reputation may partly reflect the sedating terpene profiles of aged cannabis rather than CBN itself.
Related Terms
Further Reading
More in Cannabinoids
Cannabidiol (CBD)
A non-intoxicating phytocannabinoid found in Cannabis sativa. The second most abundant cannabinoid in most cannabis strains.
Tetrahydrocannabinol (THC)
The primary psychoactive cannabinoid in cannabis. A partial agonist at CB1 and CB2 receptors.
Cannabigerol (CBG)
A non-intoxicating cannabinoid often called the "mother cannabinoid" — the biosynthetic precursor from which THC, CBD, and CBC are synthesized.
Cannabichromene (CBC)
A non-intoxicating phytocannabinoid that does not bind significantly to CB1 or CB2 receptors but interacts with TRP channels.
Phytocannabinoid
Any cannabinoid produced naturally by the cannabis plant. Distinct from endocannabinoids (produced by the body) and synthetic cannabinoids.