Interaction Database

Drug Interactions

Cannabinoid-drug interactions with severity ratings, mechanisms, clinical effects, and management recommendations. Updated quarterly.

4 Severe 5 Moderate 3 Mild

For healthcare professionals only. This database is a clinical reference tool, not a substitute for individualized clinical judgment. Always verify interactions with current prescribing information and consult a clinical pharmacist for complex cases.

12 Interactions Found

9 more drug interactions available with Professional Access

Professional Membership

For clinicians, pharmacists, and healthcare researchers

Unlock the full cannabinoid-drug interactions database — 200+ interactions with severity ratings, CYP450 mechanisms, clinical effects, and management recommendations. Updated quarterly by clinical pharmacists.

What's included

Full drug interactions database (200+ interactions)

Complete dosing protocols for 12 conditions

Clinical decision frameworks & contraindication checklists

CME-accredited modules & clinical case studies

Patient handout templates & communication guides

Weekly clinical evidence digest (clinician edition)

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CYP450 Enzyme Reference

CYP2C9

Inhibited by CBD

Key substrates: Warfarin, phenytoin, NSAIDs, sulfonylureas

CYP2C19

Inhibited by CBD

Key substrates: Clobazam, omeprazole, citalopram, diazepam

CYP3A4

Inhibited by CBD; Induced by rifampin/phenytoin

Key substrates: Tacrolimus, cyclosporine, statins, many others

Clinical Protocols Dosing Protocols