Search results for "Cannabis sleep"
25 results across studies, Q&A, topic hubs, and guides
What does current research say about cannabis and sleep quality?
Short-term use may improve sleep onset, but evidence for long-term benefit is limited. THC suppresses REM sleep; CBD shows more promise for anxiety-related insomnia without REM disruption.
Cannabis and Sleep Quality: A Meta-Analysis of Randomized Controlled Trials
Pooled analysis of 14 RCTs (n=1,847) found short-term improvements in sleep onset latency with cannabinoids, but tolerance development and rebound insomnia with prolonged use.
Sleep Disorders Research Hub
178 studies on cannabis, cannabinoids, and sleep. Covers insomnia, sleep apnea, REM behavior disorder, and circadian rhythm effects.
Cannabis Use Disorder Prevalence and Risk Factors: A Population-Level Analysis
Analysis of 42,000 participants found a 9.3% lifetime prevalence of cannabis use disorder, with early onset use and daily use patterns as the strongest predictors.
Addiction & Cannabis Use Disorder Research Hub
1,050 studies on cannabis use disorder, dependence, withdrawal syndrome, risk factors, and evidence-based treatment options including CBD and behavioral therapies.
Cannabis Researcher Profiles Directory
Profiles of the world's leading cannabis researchers — Raphael Mechoulam, Yasmin Hurd, Orrin Devinsky, Vincenzo Di Marzo, and more. Publications, h-index, active trials.
Can cannabis use affect chemotherapy outcomes?
Emerging evidence suggests cannabinoids may have anti-tumor properties in preclinical models, but clinical data on chemotherapy interactions is limited. Drug interactions with chemotherapy agents are a significant concern.
Long-Term Cognitive Effects of Adolescent Cannabis Use: A 10-Year Cohort Study
Heavy cannabis use before age 18 was associated with persistent deficits in working memory and processing speed at age 25, independent of IQ and socioeconomic factors.
Does cannabis use during pregnancy affect fetal development?
Current evidence links prenatal cannabis exposure to lower birth weight, preterm birth, and neurodevelopmental differences. No safe level of use during pregnancy has been established.
Cannabis Clinical Trials Tracker
30+ active, recruiting, and completed cannabis clinical trials — filterable by condition, phase, compound, and status. NCT IDs with direct ClinicalTrials.gov links.
Fact vs. Fiction: Common Cannabis Claims Examined
We examine 20 of the most common claims about cannabis — from "CBD cures cancer" to "marijuana is not addictive" — against the current peer-reviewed evidence.
How We Grade Evidence: Study Types & Bias in Cannabis Research
Our framework for grading scientific evidence — from RCTs and systematic reviews to preclinical studies. Includes cannabis-specific biases and how to interpret conflicting findings.
What are the long-term cognitive effects of adolescent cannabis use?
Heavy adolescent use is associated with persistent working memory and processing speed deficits. The adolescent brain is particularly vulnerable due to ongoing neurodevelopment through the mid-20s.
Cannabis Terpenes — Compound Profile
Myrcene, limonene, linalool, β-caryophyllene, α-pinene — pharmacology, the entourage effect, and 1,100+ studies on terpene-cannabinoid interactions.
CBN (Cannabinol) — Compound Profile
THC degradation product — mildly psychoactive, widely marketed as a sleep aid despite limited clinical evidence. Promising antibacterial and ALS neuroprotection data.
Yasmin Hurd, PhD — Researcher Profile
Director, Addiction Institute at Mount Sinai. Led landmark CBD RCT for heroin craving (NEJM 2019). Expert on prenatal cannabis exposure and addiction neurobiology.
Mark Ware, MBBS — Researcher Profile
Led COMPASS long-term safety study of medical cannabis. First RCT of smoked cannabis for neuropathic pain. Shaped Canadian cannabis legalization policy. McGill University.
Ziva Cooper, PhD — Researcher Profile
Director, UCLA Cannabis Research Initiative. CBD-THC interaction research. Demonstrated cannabis reduces opioid consumption. Sex differences in cannabis pharmacology.
What is the evidence for CBD in treating childhood epilepsy?
The strongest evidence in cannabis medicine. FDA-approved Epidiolex (pharmaceutical CBD) reduces seizure frequency by 40-50% in Dravet syndrome and Lennox-Gastaut syndrome in multiple RCTs.
Cognition & Memory Research Hub
1,380 studies on cannabis effects on memory, attention, executive function, and brain development — including acute impairment, adolescent risk, and potential therapeutic applications.
Reproductive Health Research Hub
620 studies on cannabis effects on fertility, pregnancy, fetal development, and breastfeeding — including prenatal exposure outcomes, sperm function, and endocannabinoid signaling in reproduction.
Raphael Mechoulam, PhD — Researcher Profile
"Father of cannabis research." Isolated THC (1964), CBD (1963), and anandamide (1992). Proposed the entourage effect. h-index 98, 62,000+ citations.
Orrin Devinsky, MD — Researcher Profile
Led pivotal Phase 3 trials of Epidiolex for Dravet syndrome and LGS (NEJM 2017, 2018). Established the first FDA-approved cannabis-derived medicine. NYU Langone.
Donald Abrams, MD — Researcher Profile
Pioneer in cannabis and oncology. First FDA-approved cannabis trial in HIV patients. RCT of cannabis for HIV neuropathy (Neurology 2007). UCSF integrative oncology.
Clinical Dosing Guidelines for Healthcare Providers
Evidence-based dosing protocols for medical cannabis and cannabinoid medications. Covers starting doses, titration schedules, and monitoring parameters by condition.