Search results for "CBD anxiety"
23 results across studies, Q&A, topic hubs, and guides
Cannabidiol as a Potential Treatment for Anxiety Disorders: A Systematic Review
A comprehensive meta-analysis of 49 studies found CBD demonstrated significant anxiolytic effects across multiple anxiety disorder subtypes, with a favorable safety profile compared to conventional pharmacotherapy.
Anxiety & PTSD Research Hub
Comprehensive index of 312 peer-reviewed studies on cannabinoids and anxiety disorders, including PTSD, GAD, social anxiety, and panic disorder.
CBD and Opioid Withdrawal: Mechanisms and Clinical Evidence
CBD attenuated opioid withdrawal symptoms in a double-blind RCT of 60 patients, reducing anxiety, cravings, and autonomic symptoms over a 7-day protocol.
THC:CBD Ratio Effects on Chronic Pain Management in Cancer Patients
Balanced THC:CBD formulations showed superior pain reduction vs. THC-only preparations in a 6-month RCT of 312 patients with cancer-related chronic pain.
CBD Bioavailability: Oral vs. Sublingual Administration Comparison
Sublingual CBD administration achieved 35% higher peak plasma concentrations compared to oral capsules, with faster time-to-peak (45 min vs. 2.1 hours) in healthy volunteers.
Does CBD interact with SSRIs and antidepressants?
CBD is metabolized by CYP2D6 and CYP3A4 enzymes, which also process many SSRIs. Current evidence suggests potential for increased SSRI plasma levels, though clinical significance varies by drug and dose.
What is the evidence for CBD in treating childhood epilepsy?
The strongest evidence in cannabis medicine. FDA-approved Epidiolex (pharmaceutical CBD) reduces seizure frequency by 40-50% in Dravet syndrome and Lennox-Gastaut syndrome in multiple RCTs.
CBD (Cannabidiol) — Compound Profile
Comprehensive pharmacology of CBD — 5-HT1A, TRPV1, GPR55 mechanisms, FDA-approved Epidiolex, drug interactions (CYP3A4/2C9), and 6,200+ indexed studies.
Understanding CBD vs. THC: What the Science Says
A plain-language guide to the differences between CBD and THC — how they interact with the endocannabinoid system, their distinct effects, and what research says about their therapeutic applications.
What does current research say about cannabis and sleep quality?
Short-term use may improve sleep onset, but evidence for long-term benefit is limited. THC suppresses REM sleep; CBD shows more promise for anxiety-related insomnia without REM disruption.
Cardiovascular Health Research Hub
890 studies on cannabinoid effects on the heart and vasculature — including THC-induced tachycardia, MI risk, CBD blood pressure effects, and cardiac arrhythmia.
Cannabinoid Pharmacology Research Hub
Bioavailability, metabolism, CYP450 interactions, and pharmacokinetics of THC, CBD, and minor cannabinoids across all routes of administration.
Yasmin Hurd, PhD — Researcher Profile
Director, Addiction Institute at Mount Sinai. Led landmark CBD RCT for heroin craving (NEJM 2019). Expert on prenatal cannabis exposure and addiction neurobiology.
Ziva Cooper, PhD — Researcher Profile
Director, UCLA Cannabis Research Initiative. CBD-THC interaction research. Demonstrated cannabis reduces opioid consumption. Sex differences in cannabis pharmacology.
Fact vs. Fiction: Common Cannabis Claims Examined
We examine 20 of the most common claims about cannabis — from "CBD cures cancer" to "marijuana is not addictive" — against the current peer-reviewed evidence.
Chronic Pain Research Hub
489 indexed studies covering neuropathic pain, cancer pain, fibromyalgia, and musculoskeletal pain. Includes dosing protocols and clinical guidelines.
Epilepsy & Seizure Disorders Research Hub
203 studies on cannabinoids and epilepsy. Includes Dravet syndrome, Lennox-Gastaut, and treatment-resistant epilepsy. FDA-approved Epidiolex data included.
Cannabis Clinical Trials Tracker
30+ active, recruiting, and completed cannabis clinical trials — filterable by condition, phase, compound, and status. NCT IDs with direct ClinicalTrials.gov links.
Orrin Devinsky, MD — Researcher Profile
Led pivotal Phase 3 trials of Epidiolex for Dravet syndrome and LGS (NEJM 2017, 2018). Established the first FDA-approved cannabis-derived medicine. NYU Langone.
Terpene Entourage Effects: A Systematic Review of Synergistic Cannabinoid Interactions
Review of 31 studies found mixed evidence for the entourage effect. Myrcene and linalool showed the most consistent synergistic activity with CBD in preclinical models.
Addiction & Cannabis Use Disorder Research Hub
1,050 studies on cannabis use disorder, dependence, withdrawal syndrome, risk factors, and evidence-based treatment options including CBD and behavioral therapies.
CBG (Cannabigerol) — Compound Profile
The "mother cannabinoid" — biosynthetic precursor to THC and CBD. Antibacterial against MRSA, neuroprotective in Huntington's disease models, anti-inflammatory in IBD.
Raphael Mechoulam, PhD — Researcher Profile
"Father of cannabis research." Isolated THC (1964), CBD (1963), and anandamide (1992). Proposed the entourage effect. h-index 98, 62,000+ citations.